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Diseases

Diseases among Cavalier King Charles Spaniel 

ALL OUR DOGS ARE AND WILL BE DNA TESTED FOR CCS & EFS BEFORE THEY ARE USED FOR BREEDING - NONE OF OUR DOGS HAVE ANY DISEASES 

- Both EFS & CCS are very bad  and can in the worst cases lead to putting the puppy to sleep 

- We have never had and ill dog or puppy 

- DNA test is from the 1.1.2012 be part of the breeding restrictions and all dogs used in breeding must be tested

- Yhe gool with the DNA test is to avoide EFS & CCS - and due to that we had all out dogs tested in july 2011

 

ALL OUR DOGS HAVE ALSO BEEN HART SCANNED - the result is to be found on every dog-page

 

Below is fact about the diseases - some are from the Danish Cavalier Klub

 

Episodic Falling Syndrome in the Cavalier King Charles Spaniel

 
 Episodic falling is a neurological condition, induced by exercise, excitement or frustration, in which muscle tone increases. This means the dog is unable to relax its muscles, becomes rigid and falls over. Affected dogs usually start to demonstrate clinical signs before one year of age, with most cases having their first episode aged four to seven months.
 
Early in 2011 Geneticists at the Animal Health Trust identified a recessive mutation associated with Episodic Falling. Episodic Falling syndrome is often difficult to diagnose as the syndrome can show similarities to other neurological conditions, such as epilepsy. A DNA test has been developed which will provide a useful diagnostic tool to the veterinary profession and dog breeders. The test will be available from 18th April 2011.
Breeders using the test will be sent results identifying their dog as belonging to one of three categories:
 
CLEAR: these dogs have two normal copies of DNA.  Clear dogs will not develop EF as a result of the identified mutation. We cannot exclude the possibility that some dogs may show some clinical signs similar to those of EF but due to a different genetic or clinical cause.
 
 CARRIER: these dogs have one copy of the mutation and one normal copy of DNA. These dogs will not develop EF themselves but they will pass the mutation on to approximately 50% of their offspring. We cannot exclude the possibility that some dogs may show some clinical signs similar to those of EF but due to a different genetic or clinical cause.
 
 AFFECTED: these dogs have two copies of the EF associated mutation and are likely to present clinical signs of EF during their lifetime, with an age of onset of around 4-7 months. EF is a highly variable condition. Our research indicates that some dogs with the EF associated mutation will not show clinical signs of EF.

 

 Dry Eye Curly Coat Syndrome in the Cavalier King Charles Spaniel

  
Dry eye and curly coat, known scientifically as congenital keratoconjunctivitis sicca and ichtyosiform dermatosis, affects a dog’s eyes and skin. Affected dogs produce no tears making their eyes incredibly sore. Their skin becomes very flaky and dry, particularly around the foot, and this can make standing and walking difficult and painful. This syndrome appears to be a problem unique to CKCS and most dogs diagnosed with the condition are put to sleep.
  
Early in 2011 Geneticists at the AHT identified a recessive mutation associated with Dry Eye Curly Coat Syndrome.  A DNA test has been developed which will provide a useful diagnostic tool to the veterinary profession and dog breeders. The test will be available from 18th April 2011.  The DNA test is specific to the mutation causing Dry Eye and Curly Coat Syndrome.
  
Breeders using the test will be sent results identifying their dog as belonging to one of three categories:
  
CLEAR: these dogs have two normal copies of DNA.  Clear dogs will not be affected by Dry Eye Curly Coat Syndrome as a result of the associated mutation identified.
  
 CARRIER: these dogs have one copy of the mutation and one normal copy of DNA. These dogs will not develop Dry Eye Curly Coat Syndrome themselves but they will pass the mutation on to approximately 50% of their offspring.
  
 AFFECTED: these dogs have two copies of the mutation associated with Dry Eye Curly Coat Syndrome and will be clinically affected.

 

 

Statistic of outcome when mating  - same for both EFS & CCS

• Clear x Clear all puppies are clear -  and no need for dna testing.

• Clear x Carrier: 50 % Carrier og 50 % Clear

• Clear x Effected: all puppies will be Effected

• Carrier x Carrier: 25 % Effected, 25 % Clear og 50 % Carrier

• Carrier x Effected: 50 % Carrier og 50 % Effected

• Effected x Effected: all puppies will be effeted  

 

 

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